منابع مشابه
Chromate transport in human leukocytes.
Chromium is a trace metal of importance in human physiology and, in addition, as 51-chromate, has been extensively used as a label in the study of blood cell pool sizes and intravascular kinetics. The transport characteristics of 51-chromate were investigated in normal human leukocytes. Chromate uptake is unidirectional over a 1 hr incubation with extracellular chromate concentrations up to 200...
متن کاملMitochondrial electron transport enzymes in normal and leukemic human leukocytes.
T HE DISCOVERY OF CHANGES in the metabolism of malignant cells, as demonstrated by enzymologic technics, will lead, hopefully, to the better understanding of the nature of the neoplastic process, which is the ultimate necessity for satisfactory therapy. In 1963, Silber, Huennekens, and Gabrio1 reported the presence of increased amounts of two pyridine nucleotide transhydrogenase enzymes in huma...
متن کاملTransport and interaction of drugs in leukocytes.
The accumulation of selected CNS drugs by rat leukocytes was previously reported. This paper presents evidence for the transport into leukocytes of additional drugs. Also studied was the inhibition of the latter processes by various structurally related compounds. The markedly rapid and sodium-independent uptakes into rat leukocytes of amphetamine, codeine, methadone and naloxone fulfilled the ...
متن کاملHeterochromatin in Human Male Leukocytes
Tritiated thymidine was added to peripheral blood cultures containing phytohemagglutinin so that DNA synthesis in interphase nuclei of white blood cells in the human male could be studied. After 57 hours in culture, a large heterochromatic body with a central position is seen in unlabeled Feulgen-stained nuclei. In labeled nuclei in which DNA synthesis was taking place in both the eu- and heter...
متن کاملEffect of famotidine on radiation induced apoptosis in human peripheral blood leukocytes
ABSTRACTBackground: Radioprotective effects of famotidine, an antagonist of H2 receptor clinically used for peptic ulcer treatment, was previously shown on radiation-induced micronuclei and chromosomal aberration in human peripheral blood lymphocytes and mouse bone marrow cells. This study was conducted to investigate radioprotective property of famotidine against radiation induced apoptosis i...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1970
ISSN: 0021-9738
DOI: 10.1172/jci106372